Publications
Chow J, Ryan N, Shefelbine SJ, Shapiro F (2023) Lamellar thickness measurements in control and osteogenesis imperfecta human bone, with development of a method of automated thickness averaging to simplify quantitation. Matrix Biol J Int Soc Matrix Biol 116:85–101.
Meslier QA, Shefelbine SJ (2023) Using Finite Element Modeling in Bone Mechanoadaptation. Curr Osteoporos Rep 21:105–116.
Comellas E, Shefelbine SJ (2022) The role of computational models in mechanobiology of growing bone. Front Bioeng Biotechnol 10:973788.
Meslier QA, DiMauro N, Somanchi P, Nano S, Shefelbine SJ (2022) Manipulating load-induced fluid flow in vivo to promote bone adaptation. Bone 165:116547.
Piet J, Adamo S, Hu D, Baron R, Shefelbine SJ (2022) Marrow aspiration in aged mice: intramedullary osteogenesis, reduced mechano-adaptation, increased marrow fat. Connect Tissue Res 63:97–111.
Comellas E, Farkas JE, Kleinberg G, Lloyd K, Mueller T, Duerr TJ, Muñoz JJ, Monaghan JR, Shefelbine SJ (2022) Local mechanical stimuli correlate with tissue growth in axolotl salamander joint morphogenesis. Proc Biol Sci 289:20220621.
Kleinberg G, Wang S, Comellas E, Monaghan JR, Shefelbine SJ (2022) Usability of deep learning pipelines for 3D nuclei identification with Stardist and Cellpose. Cells Dev 172:203806.
Ben Tahar S, Garnier J, Eller K, DiMauro N, Piet J, Mehta S, Bajpayee AG, Shefelbine SJ (2023) Adolescent obesity incurs adult skeletal deficits in murine induced obesity model. J Orthop Res 41:386–395.
Aldegaither N, Sernicola G, Mesgarnejad A, Karma A, Balint D, Wang J, Saiz E, Shefelbine SJ, Porter AE, Giuliani F (2021) Fracture toughness of bone at the microscale. Acta Biomater 121:475-483 .
Sadeghian SM, Shapiro FD, Shefelbine SJ (2021) Computational model of endochondral ossification: Simulating growth of a long bone. Bone 153:116132 .
Depalle B, McGilvery CM, Nobakhti S, Aldegaither N, Shefelbine SJ, Porter AE (2021) Osteopontin regulates type I collagen fibril formation in bone tissue. Acta Biomater 120:194-202 .
Mehta S, Young CC, Warren MR, Akhtar S, Shefelbine SJ, Crane JD, Bajpayee AG (2021) Resveratrol and Curcumin Attenuate Ex Vivo Sugar-Induced Cartilage Glycation, Stiffening, Senescence, and Degeneration. Cartilage 13:1214S-1228S .
Horenstein RE, Meslier Q, Spada JA, Halverstadt A, Lewis CL, Gimpel M, Birchall R, Wedatilake T, Fernquest S, Palmer A, Glyn-Jones S, Shefelbine, SJ (2021) Measuring 3D growth plate shape: Methodology and application to cam morphology. J Orthop Res 39:2398-2408.
Eller K, DiMauro N, Garnier J, Ruberti A, Meslier Q, Piet J, Shefelbine SJ (2021) Mechanoadaptation of the bones of mice with high fat diet induced obesity in response to cyclical loading. J Biomech 124:110569.
Kainz H, Killen BA, Van Campenhout A, Desloovere K, Garcia Aznar JM, Shefelbine SJ, Jonkers I (2021) ESB Clinical Biomechanics Award 2020: Pelvis and hip movement strategies discriminate typical and pathological femoral growth - Insights gained from a multi-scale mechanobiological modelling framework. Clin Biomech 87:105405.
Carriero A, Javaheri B, Bassir Kazeruni N, Pitsillides AA, Shefelbine SJ (2021) Age and Sex Differences in Load-Induced Tibial Cortical Bone Surface Strain Maps. JBMR Plus 5:e10467
Zando RB, Mesgarnejad A, Pan C, Shefelbine SJ, Karma A, Erb RM (2020) Enhanced toughness in ceramic-reinforced polymer composites with herringbone architectures. Compos Sci Technol 108513.
Duerr T.J., Comellas E., Jeon E.K., Farkas J.E., Joetzjer M., Garnier J., Shefelbine S.J., Monaghan J.R. (2020) 3D Visualization of Macromolecule Synthesis. eLife 9: e60354.
Horenstein R.E., Goudeau Y.R., Lewis C.L., Shefelbine S.J. (2020) Using Magneto-Inertial Measurement Units to Pervasively Measure Hip Joint Motion during Sports. Sensors 20(17): 4970.
Mesgarnejad A., Pan C., Erb R.M., Shefelbine S.J., Karma A. (2020) Crack path selection in orientationally ordered composites. Phys Rev E 102:013004 .
Kainz H., Killen B.A., Wesseling M., Perez-Boerema F., Pitto L., Garcia Aznar J.M., Shefelbine S.J., Jonkers I. (2020) A multi-scale modelling framework combining musculoskeletal rigid-body simulations with adaptive finite element analyses, to evaluate the impact of femoral geometry on hip joint contact forces and femoral bone growth. PloS One 15:e0235966 .
Sadeghian, S. M., Lewis, C. L., S. J. Shefelbine (2020). Predicting growth plate orientation with altered hip loading: potential cause of cam morphology. Biomechanics and modeling in mechanobiology, 1-12.
Main, R. P., S. J. Shefelbine, Meakin, L. B., Silva, M. J., van der Meulen, M. C., & Willie, B. M. (2019). Murine Axial Compression Tibial Loading Model to Study Bone Mechanobiology: Implementing the Model and Reporting Results. Journal of Orthopaedic Research.
Connizzo, B. K., Piet, J. M., S. J. Shefelbine, & Grodzinsky, A. J. (2019). Age-associated changes in the response of tendon explants to stress deprivation is sex-dependent. Connective tissue research, 1-15.
Kondiboyina, V., Raine, L. B., Kramer, A. F., Khan, N. A., Hillman, C. H., & S. J. Shefelbine (2020). Skeletal Effects of Nine Months of Physical Activity in Obese and Healthy-weight Children. Medicine and science in sports and exercise.
Horenstein, R. E., Lewis, C. L., Yan, S., Halverstadt, A.L. & S. J. Shefelbine (2019). Validation of Magneto-Inertial Measuring Units for Measuring Hip Joint Angles. Journal of Biomechanics, 91C, 170-174.
Woodward, R. B., Stokes, M. J., S. J. Shefelbine, Vaidyanathan, R. (2019). Segmenting Mechanomyography Measures of Muscle Activity Phases Using Inertial Data. Scientific reports 9 (1), 5569
Piet, J., Hu, D., Baron, R., & S. J. Shefelbine (2019). Bone adaptation compensates resorption when sciatic neurectomy is followed by low magnitude induced loading. Bone 120, 487-494
Doube, M., Felder, A. A., Chua, M. Y., Lodhia, K., Kłosowski, M. M., Hutchinson, J. R., & S. J. Shefelbine (2018). Limb bone scaling in hopping macropods and quadrupedal artiodactyls. Royal Society Open Science, 5(10), 180152.
Lee, J., Bubar, C., Moon, H., Kim, J., Busnaina, A., Lee, H. Y., & S. J. Shefelbine (2018). Measuring Bone Biomarker Alkaline phosphatase with Wafer-scale Nanowell array Electrodes. ACS sensors.
Chadwick, K. P., Mueske, N. M., Horenstein, R. E., S. J. Shefelbine, & Wren, T. A. L. (2018). Children with myelomeningocele do not exhibit normal remodeling of tibia roundness with physical development. Bone, 114, 292–297.
Márquez-Flórez, K., S. J. Shefelbine, Ramírez-Martínez, A., & Garzón-Alvarado, D. (2018). Computational model for the patella onset. PloS One, 13(12), e0207770.
Carriero, A., Pereira, A. F., Wilson, A. J., Castagno, S., Javaheri, B., Pitsillides, A. A., S. J. Shefelbine (2018). Spatial relationship between bone formation and mechanical stimulus within cortical bone: Combining 3D fluorochrome mapping and poroelastic finite element modelling. Bone Reports, 8, 72–80.
Kłosowski, M. M., Carzaniga, R., S. J. Shefelbine, Porter, A. E., & McComb, D. W. (2018). Nanoanalytical electron microscopy of events predisposing to mineralisation of turkey tendon. Scientific Reports, 8(1), 3024.
S. Nobakhti, and S. J. Shefelbine, (2018). On the Relation of Bone Mineral Density and the Elastic Modulus in Healthy and Pathologic Bone. Current osteoporosis reports 16(4): 404-410.
Javaheri, B., Carriero, A., Wood, M., De Souza, R., Lee, P. D., S. J. Shefelbine, & Pitsillides, A. A. (2018). Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response. Scientific Reports, 8(1), 6636.
Sheehan, F. T., Brainerd, E. L., Troy, K. L., S. J. Shefelbine, & Ronsky, J. L. (2018). Advancing quantitative techniques to improve understanding of the skeletal structure-function relationship. Journal of Neuroengineering and Rehabilitation, 15(1), 25.
Márquez-Flórez, K. M., Monaghan, J. R., S. J. Shefelbine, Ramirez-Martínez, A., & Garzón-Alvarado, D. A. (2018). A computational model for the joint onset and development. Journal of Theoretical Biology, 454, 345–356.
F. Coustry, K.L. Posey, T. Maerz, K. Baker, A.M. Abraham, C.G. Ambrose, S. Nobakhti, S. J. Shefelbine, et al., (2018). Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis. Matrix Biology 67: 75-89.
Novais, E. N., S. J. Shefelbine, Kienle, K.-P., Miller, P. E., Bowen, G., Kim, Y.-J., & Bixby, S. D. (2018). Body Mass Index Affects Proximal Femoral but Not Acetabular Morphology in Adolescents Without Hip Pathology. The Journal of Bone and Joint Surgery. American Volume, 100(1), 66–74.
Woodward, R. B., S. J. Shefelbine, & Vaidyanathan, R. (2017). Pervasive Monitoring of Motion and Muscle Activation: Inertial and Mechanomyography Fusion. IEEE/ASME Transactions on Mechatronics, 22(5), 2022–2033.
DeSouza, R., Javaheri, B., Collinson, R. S., Chenu, C., S. J. Shefelbine, Lee, P. D., & Pitsillides, A. A. (2017). Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading. Journal of Musculoskeletal & Neuronal Interactions, 17(3), 218–225
Chadwick, K. P., S. J. Shefelbine, Pitsillides, A. A., & Hutchinson, J. R. (2017). Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich. Royal Society Open Science, 4(6), 170133.
Yadav, P., S. J. Shefelbine, Pontén, E., & Gutierrez-Farewik, E. M. (2017). Influence of muscle groups’ activation on proximal femoral growth tendency. Biomechanics and Modeling in Mechanobiology, 16(6): 1869-1883.
Draghici, A. E., Potart, D., Hollmann, J. L., Pera, V., Fang, Q., DiMarzio, C. A., Taylor, J. A., Niedre, M. J., & S. J. Shefelbine (2017). Near Infrared Spectroscopy for Measuring Changes in Bone Hemoglobin Content after Exercise in Individuals with Spinal Cord Injury. Journal of Orthopaedic Research, 36(1): 183-191.
A.E. Draghici, G. Picard, J.A. Taylor, S. J. Shefelbine, (2017). Assessing kinematics and kinetics of functional electrical stimulation rowing. Journal of Biomechanics, 28(53):120-126.
Nguyen, M., Singhal, P., Piet, J. W., S. J. Shefelbine, Maden, M., Voss, S. R., & Monaghan, J. R. (2017). Retinoic acid receptor regulation of epimorphic and homeostatic regeneration in the axolotl. Development, 144(4), 601–611.
Castro-Abril, H. A., Guevara, J. M., Moncayo, M. A., S. J. Shefelbine, Barrera, L. A., & Garzón-Alvarado, D. A. (2017). Cellular scale model of growth plate: An in silico model of chondrocyte hypertrophy. Journal of Theoretical Biology, 428, 87–97.
Berteau, J.-P., Oyen, M., & S. J. Shefelbine (2016). Permeability and shear modulus of articular cartilage in growing mice. Biomechanics and Modeling in Mechanobiology, 15(1), 205–212.
Depalle, B., Qin, Z., S. J. Shefelbine, & Buehler, M. J. (2016). Large Deformation Mechanisms, Plasticity, and Failure of an Individual Collagen Fibril With Different Mineral Content. Journal of Bone and Mineral Research 31(2), 380–390.
Javaheri, B., Hopkinson, M., Poulet, B., Pollard, A. S., S. J. Shefelbine, Chang, Y.-M., Francis-West, P., Bou-Gharios, G., & Pitsillides, A. A. (2016). Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo. PloS One, 11(8), e0159657.
Li, T., Chang, S.-W., Rodriguez-Florez, N., Buehler, M. J., S. J. Shefelbine, Dao, M., & Zeng, K. (2016). Studies of chain substitution caused sub-fibril level differences in stiffness and ultrastructure of wildtype and oim/oim collagen fibers using multifrequency-AFM and molecular modeling. Biomaterials, 107, 15–22.
Osterhoff, G., Morgan, E. F., S. J. Shefelbine, Karim, L., McNamara, L. M., & Augat, P. (2016). Bone mechanical properties and changes with osteoporosis. Injury, 47 Suppl 2, S11-20.
Poulet, B., Liu, K., Plumb, D., Vo, P., Shah, M., Staines, K., Sampson, A., Nakamura, H., Nagase, H., Carriero, A., S. J. Shefelbine, Pitsillides, A. A., & Bou-Gharios, G. (2016). Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity. PloS One, 11(12), e0167971.
Ranzoni, A. M., Corcelli, M., Hau, K.-L., Kerns, J. G., Vanleene, M., S. J. Shefelbine, Jones, G. N., Moschidou, D., Dala-Ali, B., Goodship, A. E., De Coppi, P., Arnett, T. R., & Guillot, P. V. (2016). Counteracting bone fragility with human amniotic mesenchymal stem cells. Scientific Reports, 6, 39656.
Rodriguez-Florez, N., Carriero, A., & S. J. Shefelbine (2016). The use of XFEM to assess the influence of intra-cortical porosity on crack propagation. Computer Methods in Biomechanics and Biomedical Engineering, 1–8.
Yadav, P., S. J. Shefelbine, & Gutierrez-Farewik, E. M. (2016). Effect of growth plate geometry and growth direction on prediction of proximal femoral morphology. Journal of Biomechanics, 49(9), 1613–1619.
A.K. Oestreich, M.R. Garcia, X. Yao, F.M. Pfeiffer, S. Nobakhti, S. J. Shefelbine, … & C.L. Phillips, (2015). Characterization of the MPS IH knock-in mouse reveals increased femoral biomechanical integrity with compromised material strength and altered bone geometry. Molecular Genetics and Metabolism Reports 5: 3-11.
O.G. Andriotis, S.W. Chang, M. Vanleene, P.H. Howarth, D.E. Davies, S. J. Shefelbine, M.J. Buehler, & P.J. Thurner, (2015). Structure-mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model. Journal of the Royal Society, Interface/ the Royal Society 12: 111.
A.F. Pereira, B. Javaheri, A.A. Pitsillides, & S. J. Shefelbine, (2015). Predicting cortical bone adaptation to axial loading in the mouse tibia. Journal of the Royal Society, Interface / the Royal Society 12: 110.
B. Javaheri, A. Carriero, K.A. Staines, Y.M. Chang, D.A. Houston, K.J. Oldknow, J.L. Millán, B.N. Kazeruni, P. Salmon, S. J. Shefelbine, C. Farquharson, & A.A. Pitsillides, (2015). Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. Bone 81: 277-91.
M. Giorgi, A. Carriero, S. J. Shefelbine, & N.C. Nowlan, (2015). Effects of normal and abnormal loading conditions of morphogenesis of the prenatal hip joint: application to hip dysplasia. Journal of Biomechanics, 48: 12.
M.M. Klosowki, R.J. Friederichs, R. Nichol, N. Antolin, R. Carzaniga, W. Windl, S.M. Best, S. J. Shefelbine, D.W. McComb, & A.E. Porter, (2015). Probing carbonate in bone forming materials on the nanometre scale. Acta Biomaterialia, 20: 129- 139.
J.P. Berteau, M. Oyen, & S. J. Shefelbine, (2015). Permeability and shear modulus of articular cartilage in growing mice. Biomechanics and Modeling in Mechanobiology 1-8.
R.E. Horenstein, S. J. Shefelbine, N.M. Mueske, C.L. Fisher and T.A. Wren, (2015). An approach for determining quantitative measures for bone volume and bone mass in the pediatric spina bifida population. Clin Biomech 30(7): 748–754.
A. Carriero, J.L. Bruse, K.J. Oldknow, J.L> Millán, C. Farquharson, & S. J. Shefelbine, (2014). Reference point indentation is not indicative of whole mouse bone measures of stress intensity fracture toughness. Bone 69: 174-9.
B. Depalle, Z. Qin, S. J. Shefelbine, & M.J. Buehler, (2014). Influence of cross-link structure, density and mechanical properties in the mesoscale deformation mechanisms of collagen fibrils. Journal of the Mechanical Behavior of Biomedical Materials 52:1-13.
A. Carriero, E.A. Zimmerann, S. J. Shefelbine, & R.O. Ritchie, (2014). A methodology for the investigation of toughness and crack propagation in a mouse bone. Jouranl of the Mechanical Behavior of Biomedical Physics 39: 38-47.
J.P. Berteau, M. Oyen, S. Shefelbine, (2014). In vitro characterization of the elasticity and the permeability of the mouse cartilage during growth using microindentation. Computer Methods in Biomechanics and Biomedical Engineering 17: 68-9.
N. Rodriguez-Florez, E. Garcia-Tunon, Q. Mukadam, E. Saiz, K.J. Oldknow, C. Farquharson, J.L. Millán, A. Boyde and S. J. Shefelbine, (2014). An investigation of the mineral in ductile and brittle cortical mouse bone. J Bone Miner. Res. 30(5): 786–795.
A. Carriero, L. Abela, A.A. Pitsillides, S. J. Shefelbine, (2014). Ex vivo determination of bone tissue strains for an in vivo mouse tibial loading model. J of Biomechanics 47(10): 2490-7.
M. Giorgi, A. Carriero, S. J. Shefelbine, N.C. Nowlan, (2014). Mechanobiological simulations of prenatal joint morphogenesis. J of Biomechanics 47(5): 989-95.
N. Rodriguez-Florez, M.L. Oyen, S. J. Shefelbine, (2014). Age related changes in mouse bone permeability. J of Biomechanics 47(5): 1110-16.
G.N. Jones, D. Moschidou, H. Abdulrazzak, B.S. Kalirai, M. Vanleene, S. Osatis, S. J. Shefelbine, N.J. Horwood, M. Marenzana, P. De Coppi, J.H. Bassett, G.R. Williams, N.M. Fisk, P.V. Guillot, (2014). Potential of human fetal chorionic stem cells for the treatment of osteogenesis imperfecta. Stem Cells Dev 23(3): 262-76.
A. Carriero, E.A. Zimmermann, A. Paluszny, S.Y. Tang, H. Bale, B. Busse, T. Alliston, G. Kazakia, R.O. Ritchie, S. J. Shefelbine, (2014). How tough is Brittle Bone? Investigating Osteogenesis Imperfecta in Mouse Bone. J Bone Miner Res 29(6): 1392–1401.
A. Carriero, M. Doube, M. Vogt, B. Busse, J. Zustin, A. Levchuk, P. Schneider, R. Müller and S. J. Shefelbine, (2014). Altered lacunar and vascular porosity in osteogenesis imperfecta mouse bone as revealed by synchrotron tomography contributes to bone fragility. Bone 61:116-24.
A. Pereira, S. J. Shefelbine, (2014). The influence of load repetition in bone mechanotransduction using poroelastic finite element models: The impact of permeability. Biomechanics and Modeling in Mechanobiology 13(1): 215-25.
W. Macdonald and S. J. Shefelbine, (2013). Characterising neovascularisation in fracture healing with laser Doppler and micro-CT scanning. Med Biol Eng Comput 51: 1157-65.
M. Vanleene, S. J. Shefelbine, (2013). Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone. Bone 53(2): 507-14
B. Poulet, T.A.T. Westerhof, R. Hamilton, S. J. Shefelbine, A.A. Pitsillides, (2013). Spontaneous osteoarthritis in Str/ort mice is unlikely due to greater vulnerability to mechanical trauma. Osteoarthritis and Cartilage 21(5): 756-63.
N. Rodriguez, M. L. Oyen, S. J. Shefelbine, (2013). Insight into differences in nanoindentation properties of bone. J Mech Behavior of Biomed Mater 18: 90-9.
G.N. Jones, D. Moschidou, K. Lay, H. Abdulrazzak, M. Vanleene, S. J. Shefelbine, J. Polak, P. de Coppi, N.M. Fisk, P.V. Guillot, (2012) Upregulating CXCR4 in human fetal mesenchymal stem cells enhances engraftment and bone mechanics in a mouse model of osteogenesis imperfecta. Stem Cell Translational Medicine 1: 70-8.
G.N. Jones, D. Moschidou, T.I. Puga-Iglesias, K. Kuleszewicz, M. Vanleene, S. J. Shefelbine, G. Bou-Gharios, N.M. Fisk, A.L. David, P. de Coppi, P.V. Guillot, (2012). Ontological differences in first compared to third trimester human fetal placental chorionic stem cells. PloS One: 7(9): e43395.
M. Doube, S.C.W. Yen, M.M. Klosowski, A.A. Farke, J.R. Hutchinson, S. J. Shefelbine, (2012). Whole-bone scaling of the avian pelvic limb. J Anatomy 221(1): 21-9.
Carriero, A. Zavatsky, J. Stebbins, T. Theologis, G. Lenaerts, I. Jonkers, and S. J. Shefelbine, (2012). Influence of altered gait patterns on the hip joint contact forces. Comput Meth in Biomech and Biomed Eng 17: 352-59.
K.Y. Zhang, A. Wiktorowicz-Conroy, J.R. Hutchinson, M. Doube, M.M. Klosowski,S. J. Shefelbine, A.M.J. Bull, (2012). 3D morphometric and posture study of felid scapulae using statistical shape modelling. PLoS One.2012;7(4): e34619
M. Vanleene, A. Porter, P. Guillot, A. Boyde, M. Oyen, and S. J. Shefelbine, (2012). Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice. Bone 50(6):1317-23
S. Cheng, S. J. Shefelbine, and M. Buehler, (2012). Structural and mechanical differences between collagen homo- and heterotrimers: General insight and relevance for brittle bone disease. Biophysical Journal 102(3): 640-8.
O. Panagiotopoulou, S. Wilshin, E. Rayfield, S. J. Shefelbine, J. R. Hutchinson, (2011). What makes an accurate and reliable subject-specific finite element model? A case study of an elephant femur. J Royal Society Interface 9:351-61.
M. Doube, M Kłosowski, A. M. Wiktorowicz-Conroy, J. R. Hutchinson, S. J. Shefelbine, (2011). Trabecular bone scales allometrically in mammals and birds. Proceedings of the Royal Society Biology B 278:3067-73.
J. P. Moodie, K. S.Stok, R. Müller, T. L.Vincent, S. J. Shefelbine, (2011). Multimodal imaging demonstrates concomitant changes in bone and cartilage after destabilisation of the medial meniscus and increased joint laxity. Osteoarthritis and Cartilage 19(2): 163-70.
M. Vanleene, Z. Saldanha, K. L. Cloyd, G. Jell, G. Bou-Gharios, J. H. D. Bassett, G. R. Williams, N. M. Fisk, M. L. Oyen, M. M. Stevens, P. V. Guillot, S. J. Shefelbine, (2011). Transplantation of human fetal blood stem/stromal cells in the osteogenesis imperfecta mouse leads to improvement in multi-scale tissue properties. Blood 117(3): 1053-60.
M. Doube, M. M. Kłosowski, I. Arganda-Carreras, F. P. Cordelières, R. P. Dougherty, J. S. Jackson, B. Schmid, J. R. Hutchinson, S. J. Shefelbine, (2010). BoneJ: Free and extensible bone image analysis in ImageJ. Bone 47(6): 1076-9.
B. Poulet, R. W. Hamilton, S. J. Shefelbine, A. A. Pitsillides, (2010). Characterising a novel and adjustable non-invasive murine knee joint loading model. Arthritis Rheum. 63(1): 137-4.
A. Carriero, I. Jonkers, S. J. Shefelbine, (2010). Mechanobiological prediction of proximal femoral deformities in children with cerebral palsy. Computer Methods and Biomedical Engineering 14(3): 253-62
P. Sztefek, M. Vanleene, R. Olsson, R. Collinson, A. A. Pitsillides, S. J. Shefelbine, (2010). Using digital image correlation to determine surface strains during loading and after adaptation of the mouse tibia. Journal of Biomechanics 43: 599-605.
M. Doube, A. Wiktorowicz Conroy, P. Christiansen, JR Hutchinson, S. J. Shefelbine, (2009). Three-dimensional geometric analysis of felid limb bone allometry. Public Library of Science (PLoS) One. 4(3) e4742. (link to pdf)
A. Carriero, A. Zavatsky, J. Stebbins, T. Theologis, S. J. Shefelbine, (2009). Correlation between lower limb bone morphology and gait characteristics in children with spastic diplegic cerebral palsy. Journal of Paediatric Orthopaedics. 29(1):73-9.
A. Carriero, A. Zavatsky, J. Stebbins, T. Theologis, S. J. Shefelbine, (2009). Determination of gait patterns in children with spastic diplegic cerebral palsy using principal components. Gait and Posture. 29(1):71-5.
R. D. Carpenter, S. J. Shefelbine, J. Lozano, K.Y. Lee, S. Majumdar, B. Ma, (2008). A New Device for Measuring Knee Rotation in ACL-Deficient Patients. Journal of Medical Devices, 2: 44501-1.
P.V. Guillot, O. Abass, J.H. Bassett, S. J. Shefelbine, G. Bou-Gharios, J. Chan, H. Kurata, G.R. Williams, J. Polak, N.M. Fisk, (2008). Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice. Blood, 111: 1717 – 1725.
S. J. Shefelbine, S. Majumdar, (2005). Imaging bone structure and osteoporosis using MRI. Clincal Cases in Min and Bone Metabolism 2(2):119-26.
S. J. Shefelbine, B. Ma, K.Y. Lee, M.A. Schrumpf, P. Patel, M.R. Safran, J.P. Slavinsky, S. Majumdar, (2006). MRI Analysis of in vivo meniscal and tibiofemoral kinematics in ACL-deficient and normal knees. Journal of Orthpaedic Research. 24(6): 1208-17.
Sarkar, M. R., P. Augat, S. J. Shefelbine, S. Schorlemmer, M. Huber-Lang, L. Claes, L. Kinzl, A. Ignatius, (2005). Bone formation in a long bone defect model using a platelet-rich plasma-loaded collagen scaffold. Biomaterials 27(9): 1817-23.
S. J. Shefelbine, P. Augat, L. Claes, and U. Simon, (2005). Trabecular bone fracture healing simulation with finite element analysis and fuzzy logic. Journal of Biomechanics 38(12): 2440-50.
S. J. Shefelbine, P. Augat, L. Claes, A. Gold, Y. Gabet, I. Bab, and R. Müller, (2005). Prediction of fracture callus mechanical properties using microCT images and finite element analysis. Bone 36(3): 480-8.
S. J. Shefelbine, P. Augat, L. Claes, and A. Beck, (2005). Intact fibula improves fracture healing in a rat tibia osteotomy model. Journal of Orthopaedic Research 23(2): 489-93.
S. J. Shefelbine and D. R. Carter, (2004). Mechanobiological predictions of femoral anteversion in cerebral palsy. Annals of Biomedical Engineering. 32(2): 297-305.
S. J. Shefelbine and D. R. Carter, (2004). Mechanobiological predictions of growth front morphology in developmental hip dysplasia. Journal of Orthopedic Research 22(2): 346-52.
S. J. Shefelbine, C. Tardieu, and D. R. Carter, (2002). Development of the femoral bicondylar angle in hominid bipedalism. Bone 30(5): 765-70.
Books
A.E. Draghici, S. J. Shefelbine, (2016). Increased Bone Fracture After SCI: Can Exercise Reduce Risk? The Physiology of Exercise in Spinal Cord Injury, 161-174.
S. J. Shefelbine, J. Clarkson, R. Farmer, S. Eason. Good design practice for medical devices and equipment – requirements capture. Institute for Manufact